Patient Resources

Post-Tubal Ligation Syndrome (PTLS)

Post-Tubal Ligation Syndrome (PTLS) consists of a variety of symptoms that may include heavy or missing menstrual periods, hormonal problems, or problems that mimic menopause. These symptoms are reported by some women after receiving a tubal ligation procedure. Symptoms may also include mood swings, hot flashes, anxiety, depression, fatigue, sleep problems, and vaginal dryness, among others. Symptoms range from mild to severe and can be extensive. 

What Is Post-Tubal Ligation Syndrome?

Most symptoms that arise after tubal ligation are limited to the pelvis and involve changes in the menstrual cycle or pelvic discomfort. PTLS symptoms are more widespread and involve areas of the body not commonly associated with female reproductive organs. Women that report symptoms often report migraines, hair/nail/skin changes, joint pains, abdominal pain, and many other symptoms.

This syndrome is thought to occur as a direct result of a tubal ligation procedure. Roughly 37% of women suffer from Post-Tubal Ligation Syndrome following tubal ligation surgery. Of that 37%, women who have had their tubes cauterized at a younger age are at a higher risk for this syndrome. 

Post-Tubal Ligation Syndrome has been linked with other medical issues, including:

  • Castrative menopause
  • Ovarian Isolation
  • Imbalances of hormones or hormone shock
  • Dysfunctional uterine bleeding
  • Increased risk of heart disease
  • Severe pelvic adhesions
  • Bone loss/osteoporosis
  • Misplacement of female organs


Treatment for PTLS includes a tubal ligation reversal. Many patients that have received a reversal have reported an improvement in their overall health and well-being. At NCCRM, a tubal ligation reversal is done as an outpatient procedure. 


The North Carolina Center for Reproductive Medicine/Talbert Fertility Institute is the premiere center for reproductive health in North Carolina and the East Coast. Our team specializes in fertility testing, diagnosis, and treatment of infertility conditions. We’re experts in IVF, Tubal Ligation Reversal, Male Infertility, Intrauterine Insemination (IUI), Gestation Surrogacy, Family Balancing and more. At NCCRM, we can help you with your PTLS symptoms by performing a Tubal Reversal. Get started by clicking here.

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